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Literature summary extracted from

  • Chen, J.; Chen, Y.; He, Q.
    Action of bleomycin is affected by bleomycin hydrolase but not by caveolin-1 (2012), Int. J. Oncol., 41, 2245-2252.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.4.22.40 bleomycin + H2O Homo sapiens
-
?
-
?

Organism

EC Number Organism UniProt Comment Textmining
3.4.22.40 Homo sapiens
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.22.40 HaCaT cell
-
Homo sapiens
-
3.4.22.40 HeLa cell
-
Homo sapiens
-
3.4.22.40 Hep-G2 cell
-
Homo sapiens
-
3.4.22.40 HL-60 cell
-
Homo sapiens
-
3.4.22.40 L-02 cell
-
Homo sapiens
-
3.4.22.40 liver
-
Homo sapiens
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.22.40 bleomycin + H2O
-
Homo sapiens ?
-
?

Synonyms

EC Number Synonyms Comment Organism
3.4.22.40 BLH
-
Homo sapiens

General Information

EC Number General Information Comment Organism
3.4.22.40 malfunction the sensitivity to bleomycin is increased in HeLa cells after knockdown of bleomycin hydrolase Homo sapiens